The brain is the organ in the body that ages faster and more significantly than all other tissues in the body. The motive for this event is inherently correlated to biochemistry and brain purpose. As a result, once they die, they are not replaced by new cells. Furthermore, it must be remembered that brain is a structure with a high energy metabolism. In fact, the brain uses large quantities of oxygen, highly reactive substances. Check out the Noocube results.
The brain in some areas also has a high concentration of iron and copper, metals that are able to catalyze the production of very harmful radical forms (Fenton reaction). Furthermore, and this is almost a paradox, the brain has a very low concentration of endogenous antioxidants (protein and non-protein). For example, the levels of glutathione, superoxide dismutase and catalase are about 1/5 of those in the liver. In fact, therefore, the brain is by its nature extremely exposed to oxidative stress and consequently ages more prematurely than other tissues.
In recent years, the incidence of neurodegenerative diseases, and in particular Alzheimer’s disease, has been increasing exponentially in industrialized countries, and also in developing countries. The latest data presented by the Alzheimer’s Association speak of a tripling of Alzheimer’s cases from now to 2050, and by that date it is expected that one in three elderly people in the Western world will be affected by Alzheimer’s. These are huge numbers, unsustainable for any health system. In this perspective of socio-health emergency, the possible availability of substances that increase the natural defenses of the brain, slowing down the death of neurons and preventing the onset of cognitive pathologies is increasingly important.A